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If there are no GI AEs, then, in the authors’ clinical experience, up‐titration may be performed rapidly, for example, increasing to the next dose after 2‐4 weeks, although the lower end of this range may not be in accordance with the product label and cost may need to be considered when deciding on an up‐titration schedule

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If hemoglobin is low or low-normal, add iron studies (ferritin, serum iron, TIBC, transferrin saturation)